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Biopsies can also be taken from the gut, bladder or skin, where the presence of high or abnormal mast cell numbers can be supportive of a diagnosis of MCAS or mastocytosis

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Importantly, this anti-inflammatory action does not suppress immune function entirely like corticosteroids often do

This case underscores the importance of recognizing how GLP-1 RA-induced motility changes can interact with pre-existing risk factors, highlighting the need for careful patient selection, close monitoring, and early intervention in high-risk individuals