"Semaglutide, the active ingredient in Ozempic, mimics GLP-1, a hormone that helps regulate blood sugar levels and makes you feel fuller for longer," explains Caroline Apovian, MD, Co-Director of the Center for Weight Management and Wellness at Brigham and Women's Hospital
Additionally, literature has reported that ALA can inhibit RANKL-induced osteoclastogenesis via the FFAR4/arr2 signaling pathway and prevent inflammation, which is consistent with the findings of this study [37]
Bioactive Compounds Omega-3s, medium-chain fats, berberine, curcumin, and capsaicin can enhance GLP-1 secretion or slow its breakdown by inhibiting DPP-4 the same enzyme targeted by DPP-4 inhibitor drugs
(The recommended dose for hypothyroidism in the 2016 study referenced earlier was 1800 mg per day