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Common issues reported in clinical studies include nausea, diarrhea, and mild gastrointestinal discomfort

Most patients tolerate the medications well after the initial adjustment period

note that lactulose is not recommended as it may worsen bloating [14] [18] For abdominal pain : Antispasmodics (mebeverine, peppermint oil) taken before meals For global symptoms : Tricyclic antidepressants at low doses, with selective serotonin reuptake inhibitors (SSRIs) considered if TCAs are ineffective or not tolerated Psychological therapies have robust evidence in IBS management, including cognitive behavioural therapy (CBT), gut-directed hypnotherapy, and mindfulness-based interventions

SLU-PP-332 regularly gets purity levels above 99.8%, which means it can be used to make active medicinal ingredients