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This increased glutathione pool may help contend with the increased flow of free radicals from dysfunctional mitochondria

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67 This finding was reaffirmed in another study that demonstrated a corresponding increase of serum miRNA-122 and miRNA-375, along with an increase in APAP protein adducts, all of which were also seen prior to ALT elevation

doi: 10.3803/EnM.2022.1629 4 TuttleKRAgarwalRAlpersCEBakrisGLBrosiusFCKolkhofPet al