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Often, these individuals possess dysfunctional mutations in one or more enzymes related to glutathione function

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The liver depends on intracellular glutathione for detoxification and that requires the compound to actually reach liver cells intact

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However, the results of this studyindicate that the alterations caused by riboflavin deficiency lie not only at the enzymatic activity level, but also at the protein expression level for the flavin-containing enzymes

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