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This complex system (often referred to as the IGF "axis") consists of two cell-surface receptors (IGF1R and IGF2R), two ligands (IGF-1 and IGF-2), a family of seven high-affinity IGF-binding proteins (IGFBP1 to IGFBP7), as well as associated IGFBP degrading enzymes, referred to collectively as proteases

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By acting on these pathways, it helps to regulate insulin stashing, control blood sugar situations, and promote weight loss

G6PD-deficient AA subjects showed elevated levels of OS and decreased levels of glutathione (GSH) [7]