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Based on our previous study [8] and this study, we hypothesized that the perforin gene promoter in CD4 + T lymphocytes in rats with autoimmune emphysema was hypomethylated, which could activate perforin genes to promote the production of AECA and increase alveolar septal cell apoptosis, thereby contributing to the development of autoimmune emphysema in rats

The recommended daily intake of collagen is around 3,000 to 6,000 mg

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