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Conversely, Ramezani-Moghadam and colleagues have demonstrated that adiponectin increases TIMP-1 expression to initiate the MMP-independent signaling cascade through the CD63/1-integrin complex, leading to the reduction of focal adhesion kinase phosphorylation, thereby limiting HSCs cell migration [180]

Additionally, studies have found that GHK-Cu promotes the proliferation of keratinocytes and fibroblasts, speeding up wound closure and tissue repair (2)

Growth hormone deficiency, thyroid dysfunction, and cortisol dysregulation are common after stroke and each independently impairs neuroplasticity