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Its involvement at the intersection of metabolic regulation, stress responsiveness, and reproductive endocrinology positions it as a candidate for conditions in which these domains converge, such as menopause-associated metabolic dysfunction or stress-related eating disorders

Efficacy of brodalumab in the treatment of scalp and nail psoriasis: results from three phase 3 trials

On the other hand, in around 40% of cases of male infertility, the issue is directly related to reduced sperm motility, known as asthenozoospermia

Therefore, it is hypothesized that ghrelin synthesized within the hypothalamus, as opposed to gut-derived ghrelin, is the mediator of central orexigenic effects of ghrelin, although further research is needed 224