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Compliance with Ethics Guidelines The trial enrolled subjects at a single site in China (the Clinical Trial Center, Beijing Hospital, Beijing) and was approved by the Ethics Committee of Beijing Hospital

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Human and Animal Rights All reported studies/experiments with human or animal subjects performed by the authors have been previously published and complied with all applicable ethical standards (including the Helsinki declaration and its amendments, institutional/national research committee standards, and international/national/institutional guidelines)

A P value 1.5 or FC To investigate the effects of GLP-1R activation on silica-induced pulmonary fibrosis, mice were intratracheally instilled with a single dose of silica, followed by daily treatment with the GLP-1R agonist liraglutide for 56 days