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Understanding and addressing irAEs is a pressing issue for another reason as well: given that only about a third of cancer patients respond to immune checkpoint inhibitors, research labs and pharmaceutical companies are doubling down on efforts to expand the efficacy to more patients, and one of the approaches is to combine different immunotherapeutics to target different pathways

Balaban YH, Korkusuz P, Simsek H, Gokcan H, Gedikoglu G, Pinar A, et al

The trade-off to consider: Enterokinase is a heterodimeric serine protease, adding some complexity to its own production and handling

+ If you are genuinely low in B12, an injection can lift the fatigue, brain fog and sluggishness that deficiency causes, which many people feel as a clear energy boost