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Some learn to ignore hunger, fullness, fatigue, or pain because paying attention never felt particularly safe

Over time, this may contribute to sarcopenia: age-related muscle loss associated with reduced physical function, increased risk of falls, and other adverse health outcomes

28, 2025, semaglutide (Ozempic) received FDA approval to reduce the risk of kidney disease worsening, kidney failure (end-stage kidney disease) and death due to cardiovascular disease (CVD) in adults with type 2 diabetes (T2DM) and chronic kidney disease (CKD)

The FDA requires this warning based on animal data, and notes that it is unknown whether these medications cause thyroid C-cell tumors, including medullary thyroid carcinoma, in humans