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Vitamin B12 injections can be particularly beneficial for several groups of individuals who may have difficulty obtaining adequate levels of this essential nutrient through diet alone

However, a number of factors, including dose, formulation, and type of study population, affect the bioavailability of tocotrienols and may undermine their putative efficacy in humans (14)

Human evidence for precursors is mixed: some trials report good safety, but metabolic endpoints such as insulin sensitivity have not consistently replicated in people