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Notably, depending on the deficiencys severity, patients may need five (5) to seven (7) shots in their first week of treatment

Sep 2022;31(3):567-578

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Due to the high expression profile of GLP-1R in pancreatic -cells, GLP-1 analogs (such as exendin-4) have been modified by different methods (to prolong half-life, maintain receptor binding affinity and reduce renal drug accumulation) for theranostic purposes and serve as excellent templates for future cardiovascular drug development[178-184]