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High-dose oral supplementation may be another treatment option, because consuming 1,000 g (1 mg) per day of vitamin B 12 orally should result in the absorption of about 10 g/day (1% of dose) by passive diffusion

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That means: 1 unit = 0.01 mL 10 units = 0.1 mL 50 units = 0.5 mL 100 units = 1.0 mL The "U-100" designation refers to the insulin concentration the syringe was designed for, not anything about peptides