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The tissue concentrations are presented in ng/g tissue, which was calculated as the measured concentration in the tissue homogenate by LCMS/MS (ng/mL) divided by the density of tissue homogenate (g tissue/mL) (Song et al

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For researchers and clinicians following this issue, this is the central question in the upcoming FDA decision: is dysesthesia frequent and debilitating enough to justify a special mention in the indications, or even a 12 mg dose reserved for specific patients