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[5] On May 5, 2010 the Italian Medicines Agency (AIFA - Agenzia Italiana del Farmaco) became the first governmental health organization ever (even before the drug received approval in Europe) to authorize afamelanotide as a medicine for therapeutic treatment of Italian citizens to reduce painful photosensitivity stemming from the orphan disease erythropoietic protoporphyria (EPP)

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Advances in Gerontology = Uspekhi Gerontologii

Our study thus reveals a pathogenic mechanism in which zinc accumulation induces -cell identity loss through lineage-tracing approaches and proposes a protective strategy to counteract this process