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Clinical Evidence: Semaglutide Trials Show Insulin Improvement and Weight Loss The SUSTAIN-6 trial, which followed over 3,000 participants for two years, demonstrated that semaglutide reduced HbA1c (a marker of average blood glucose control) by 1.41.5 percentage points while producing weight loss averaging 46 kg

10.15252/embj.201488104 EMBO J

While transitional assistance has stepped in for some, nearly 60% of written GLP-1 prescriptions remained unfilled in the first half of 2023

Heres a concise overview of its benefits for weight loss, based on available data: Substantial Weight Reduction: Clinical trials, such as SURMOUNT-1, demonstrate that tirzepatide leads to significant weight loss