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Extensive Clinical Application of GLP-1RAs GLP-1RAs for the Treatment of T2DM GLP-1RAs are well established for the management of T2DM, and their clinical efficacy has been extensively investigated and validated

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Retatrutide is an investigational triple receptor agonist targeting GLP-1, GIP, and glucagon receptors not yet licensed by the MHRA or EMA for use in the UK