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The first few months show the fastest loss, followed by a gradual deceleration as you approach a new metabolic equilibrium

Focus on nutrient-dense foods that provide sufficient protein (generally 0.8-1.2 grams per kilogram of body weight daily, as recommended by a healthcare provider), complex carbohydrates, and healthy fats

All outcomes and analyses were prespecified, with the exception of the estimated BV and PV, as well as the regression analyses used to explore potential mechanisms, so these data should be treated as hypothesis-generating

In the published case series, one patient was successfully treated with pilocarpine 5 mg daily