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This review delineates the multifaceted mechanisms by which GLP-1RAs exert ocular benefits, including retinal ganglion cell (RGC) rescue via calcium channel and GABAergic modulation, mitochondrial protection through PINK1/Parkin-mediated mitophagy and ERK1/2-HDAC6 signaling, as well as potent anti-inflammatory effects via cytokine reduction and immune cell recruitment inhibition

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There is now a pressing need for data collection, and many important scientific questions that still need to be addressed

Patient Support and Education: Novo Nordisk has initiated or expanded patient support programs, providing educational materials, support lines, and resources to help users understand and manage potential side effects