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Semaglutide (Ozempic or Wegovy) and liraglutide (Saxenda or Victoza) have shown promising results in small studies for improving metabolic markers in PCOS

The nausea tends to be worse in the morning before eating and immediately after meals, while sulfur burps are typically most frequent 1 to 3 hours after eating

For instance, in a randomised, placebo-controlled, double-blind Phase I study of ascending single doses of cotadutide in healthy individuals with overweight, there were dose-dependent improvements in glucose excursions post meal within 24 h and food intake reduction after a single dose of 100 g [82]