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Immunogenic cell death (ICD) ICD is a form of cell death that elicits a potent immune response, typically triggered by cancer treatments (such as chemotherapy and radiotherapy) [260]

Research has found that GLPs regulate the microbial communities inside the mouth, intestines, pancreas, and lungs of rats suffering from T2DM by significantly increasing abundance of beneficial bacteria such as * Lactobacillus *, * Bifidobacterium *, * Prevotella *, * Blautia *, selenium-rich bacteria, along with * Coprococcus *, in addition to by inhibiting harmful bacteria such as * Staphylococcus *, * Escherichia *, * Ruminococcus torques (Holdeman and Moore 1974)*, * Streptococcus mutans (Clarke 1924)*, and *Clostridium perfringens (Veillon and Zuber 1898) * , consequently bettering glucose metabolism disturbances and alleviating reduced sensitivity to insulin (Li M

Ambruso, S