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I got people off of their PPIs and Zantac just by doing a three month course at BPC 157

A randomized, controlled study evaluating effects of amlodipine addition to chelators to reduce iron loading in patients with thalassemia major

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While high sheer stress caused by vasoconstriction is considered atheroprotective during the early phases of atherogenesis, it later predisposes individuals to more vulnerable plaque phenotypes that cause MI and stroke 42