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2 Molecular mechanisms of GLP-1 Action 2.1 GLP-1 Receptor structure and signalling The GLP-1 receptor (GLP-1R), a G-protein-coupled receptor, activates a complicated signalling cascade upon the interaction of GLP-1 (Fig

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Important Jobs for GLP-1: Signals fullness to your brain , helping you feel satisfied after eating

Here, we review the role of GLP-1 and the actions of associated therapies on glucose metabolism, the gutrenal axis, classical renal risk factors, and renal end points in randomized controlled trials of GLP-1 receptor agonists and DPP-4 inhibitors in patients with T2DM