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Chang PP, Wruck LM, Shahar E, et al

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The Wegovy FDA prescribing label explicitly states: "Semaglutide causes a delay in gastric emptying, and thereby has the potential to impact the absorption of concomitantly administered oral medications." [3] That warning is generic, but it has direct implications for time-sensitive drugs like oral contraceptives (more on that below) and for drugs like ibuprofen whose mucosal contact time is now extended