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However, intervention measures such as antioxidant therapy, depletion of Kupffer cells, knockout of the Tnfr1 gene, or inhibition of JNK activity can effectively reduce the incidence of precancerous lesions in bile duct cells (107)

NNF Grant number: NNF20CC0035580, DFF and Thematic Research-Independent green research (2023): 316400026 A

It is also important to note that they should be taken alongside a total weight loss program

11 Its also important to note that taking B12 in combination with vitamin B6 and folate (rather than alone) is shown to be most effective for regulating homocysteine levels for some patients and preventing the combined risk of stroke, myocardial infarction (heart attack), and damage to heart cells