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TRPM4 knockdown substantially reduced cellular inflammation, oxidative stress, and lipid peroxidation, thereby improving endothelial function and potentially modulating atherosclerosis progression

For individuals with significantly depleted levels, the route of administration matters even more

The involvement of particular amino acids, like arginine, within the CCP is crucial in the targeting procedure as the positively charged guanidine group in arginine can bind to negatively charged components of bacteria cell membranes, helping in the entry and uptake of NPs [213, 214]

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