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Description

The cyclic structure of Melanotan-2 confers greater metabolic stability but also reduces receptor selectivity, leading to its broad melanocortin receptor activation profile

M.NbregaM

This process may be a characteristic of xCT high cancer cells

We found that pharmacological MT1 and MT2 agonism failed to replicate the effects of melatonin in suppressing IL-5 production ( Figures 3B, D ) or IL-13 production ( Figures 3C, E )