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2 Current management of NTHi infections necessitates alternative therapeutic strategies 2.1 Antibiotic therapy NTHi-associated lower respiratory infections are typically treated with moderate spectrum -lactam (typically amoxicillin or amoxicillin-clavulanic acid) antibiotics (Marchant et al., 2024)

Earlier phase 1 and 2 studies demonstrated that cagrilintide was well-tolerated, exhibiting a safety profile consistent with FDA-approved GLP-1 receptor agonists like semaglutide and liraglutide, as well as the amylin analog pramlintide [1]

Regulatory and safety status: Ipamorelin is pending FDA review

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