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doi:10.1038/clpt.2010.184 Lyssenko V, Lupi R, Marchetti P et al (2007) Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes

B vitamins are often depleted in individuals with substance abuse, particularly alcohol abuse, due to poor nutritional intake, increased demand for metabolizing substances and poor gastrointestinal absorption

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9 Importantly, PCOS is a diagnosis of exclusion, meaning that other causes of ovarian dysfunction and hormone imbalance must be excluded to confirm a diagnosis