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This response promotes proper nutrient metabolism by increasing glucose utilization in insulin-dependent tissues such as muscle and adipose tissue, reducing endogenous glucose production, and enhancing glycogen synthesis

Although serum sampling offers a broader picture of metabolism after TBI and lacks the specificity of cerebral microdialysis approaches, it clearly shows promise as a feasible enhancement to established models of prognostication based on clinical features

22,149,150 TSC1 acts as a regulator of the stability of TSC2, preventing the degradation of TSC2, while TSC2 is a GTPase activating protein (GAP) that inactivates Rheb, a GTPase of the Ras family, and other small G proteins

Mitmesser, S