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Consistent with previous reports, participants with fusion-positive AML presented at a younger age of onset compared to those with NPM1 -mutant or MDS-related AML (Supplementary Table 1)

The presence of tinnitus does not cause these diseases but it could indicate brain alterations that occur before disease onset and it might share common risk elements with hearing damage, diabetes, and head trauma

T3 levels are diet sensitive and have a positive correlation with basal metabolic rate 42

Oral GLP-1 tablets are also becoming available and offer a needle-free alternative, though injectable forms remain the most established and widely prescribed option in the UK