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Clinical manifestations include cardiomyopathy, skeletal myopathy, arrhythmia, hyperlipidemia, as well as hypotension and muscle cramps during dialysis

On its own, cagrilintide has shown clinically meaningful weight loss (11 to 12%) with a tolerability profile that analysts have highlighted as one of its key strengths

Medical weight loss treatments, both oral and injectables, offer a promising alternative to those trapped in this cycle

Moreover, glucocorticoid-induced inhibition of monocyte-dependent proliferative responses may be prevented by IL-2 administration [84], and IL-1 may counteract the inhibitory effects of glucocorticoids on purified T cells [85]