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Thickened Skin : The skin in these areas becomes thickened and may have a velvety texture

It does not activate the hGH receptor or raise IGF1 levels, and it has no meaningful effect on blood glucose or insulin sensitivity

According to Table 1, comprehensive experimental and observational studies reveal that GLP-1RAs do not elevate overall cancer risk, while preclinical investigations have demonstrated multiple anti-tumor mechanisms, including proliferation inhibition, apoptosis induction, and metastasis suppression