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Three serious adverse events were considered to be treatment related and there were 4 adverse eventrelated discontinuations

bw, body weight

For instance, supplementation of immature mouse testicular cultures with 5% PRGF was associated with enhanced production of flagellated sperm and increased markers of germ cell proliferation and differentiation, such as PLZF, SYCP3, ACRBP, and Ki67, along with reduced Bax expression (34)