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A large share of glutathione Chemist Warehouse searches are really skin searches, so precision matters: a randomised, double-blind, placebo-controlled study in Clinical, Cosmetic and Investigational Dermatology ran twelve weeks with 250mg a day and found melanin index and ultraviolet spots trended lower than placebo, with modest gains in elasticity (Weschawalit et al., PMID 28490897)