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albicans strains used in this study are presented and described in Supplementary Table 1

As analytical technologiessuch as LCMS/MS quantification, microdialysis, and in situ perfusioncontinue to refine measurement precision, researchers are now able to characterize intestinal uptake mechanisms and degradation pathways at unprecedented detail

The rate-limiting enzyme in GABA synthesis, GAD, is found only in neurons, thus establishing this cell type as the likely primary site of estradiol action where it increases the activity of GAD, and thereby the synthesis of GABA, which is released from neurons to act on neighboring astrocytes to induce stellation