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While not directly causing constipation, gallbladder issues can present with abdominal pain that might be confused with other GI discomfort

However, there was a statistically significant reduction in the risk of hypoglycemia by about 30% [RR=0.70, 95% CI (0.57, 0.87), p =0.001] ( Figure 4 ), and pneumonia by about 25% [RR=0.85, 95% CI (0.75, 0.97), p =0.01] ( Figure 5 )

What we should not do is take a wait-and-see position, hoping that research groups will come along to propose and scrape together funding for long-term trials that may not give us actionable results before 2030

If weight loss is your primary goal, Mounjaro (tirzepatide) and Wegovy (semaglutide 7.2 mg) are the licensed options in the UK