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some patients resume after symptoms resolve, others wait 2448 hours

Lactate then gets shuttled into neurons, and the reason why neurons like that is because it's thermodynamically favorable, much like beta-hydroxybutyrate which you mentioned, BHB, because it can shunt right into the TCA cycle in the mitochondria

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Another common hurdle is step therapy, which forces you to try and fail with cheaper, older medications before the plan will cover a newer, more expensive one like a GLP-1