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In a larger 36-week trial with children, caregiver ratings indicated substantial improvements in irritability, but measures of overall autism severity, like the Ohio Autism Clinical Impressions Scale (OACIS), showed only small, non-significant gains

Following chronic (6 week) feeding with an ethanol-containing liquid diet, the Gclm KO mice were unexpectedly found to be protected against steatosis despite showing increased oxidative stress (as reflected in elevated levels of CYP2E1 and protein carbonyls)

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