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For these reasons, antibiotic treatment is often insufficient to prevent relapse caused by persistent bacterial communities and does not offer long-term protection against reinfection with different strains, particularly in COPD airways (Leibovitz, 2008

D- Perspectives The elimination of senescent cells in a pathological context appears more complicated than anticipated, especially because of the physiological function of senescence in normal tissues

subtilis was found to further exhibit anti-aggregation properties by regulating the sphingolipid metabolic pathway involving upregulation of LAGR-1/CERS1 (ceramide synthase), ASM-3/SMPD1 (acid sphingomyelinase), and downregulation of SPTL-3/SPTLC2 (serine palmitoyltransferase), therefore, reducing glucosylceramide ( In PD and AD individuals, an increased abundance of Enterobacteriaceae taxa, particularly Escherichia coli , is associated with increased concentrations of LPS and the bacterial amyloid protein curli (Scheperjans et al., 2015

Toxicology 209(1):6976