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GLP-1 receptor agonists and related incretin-based peptides reduce HbA1c, body weight and certain cardiovascular risk markers in appropriate patients, especially when combined with nutrition and activity interventions

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There was also a higher risk of incidence of biliary disease, but the researchers said it was not statistically significant. Although these side effects are rare, the studys authors said because millions of people around the world use the drugs, it could lead to hundreds of thousands of people experiencing these conditions. Get weekly health news The exact number of Canadians using these weight loss drugs is not known, but Ozempic has become so popular that in August, its manufacturer, Novo Nordisk, announced a shortage of the medication in Canada