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Mycotoxin Effect on Immunity is Oxidative Stress Related AFB1 mainly affects cell-mediated immunity and has also been shown to increase inflammation [85]

The AF4 family/ENL family/P-TEFb complex (AEP) binds to acetylated H3K9/18/27 to activate transcription, consequently activating the cellular machinery required for aberrant self-renewal of leukemia stem cells

The assay was validated according to local procedures: the FDA 2018 guideline on validation of bioanalytical methods [17], the EMA 2011 guideline on validation of bioanalytical methods [18] and current practice

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