La estabilidad gstrica intrnseca del pptido y su secuencia rica en prolina lo hacen ms resistente a la degradacin enzimtica que la mayora de los pptidos, pero sigue siendo necesario refrigerar
The key protease responsible for the processing of the proglucagon peptide into GLP-1 is Psck1/3, which has shown to be upregulated in -cells during hyperglycaemic, hyperlipidemic, or inflammatory conditions to promote glucose-induced glucagon suppression, a compensatory response to a metabolic insult as in type 2 diabetes (205)
10.1158/1078-0432.CCR-19-3975 250 YangJ.ZhouY.XieS.WangJ.LiZ.ChenL.et al (2021)
Fat-dissolving injections, on the other hand, are best suited for non-surgical body contouring of small, stubborn fat pockets, like under the chin, knees, or upper arms