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However, because carnitine transport into the muscles is heavily mediated by insulin, some functional medicine practitioners recommend taking it alongside a small amount of complex carbohydrates to trigger a mild insulin response, which actively drives the carnitine into the muscle cells

Specifically, berberine can cause: Nausea Diarrhea Stomach cramps Bloating Headache Constipation (particularly when you stop taking it) Rashes (though this is relatively rare) The more berberine you take, the more likely you are to experience these side effects

This work represents a clinically tractable intervention to non-invasively preserve ovarian function and female fertility during chemotherapy without diminishing the efficacy of cancer treatment, potentially acting as a fertoprotective neoadjuvant agent (Woodruff, 2017) to improve the long-term health and quality of life of cancer survivors