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Because CDT B toxin and vinculin look similar, the immune system mistakenly targets the body's vinculin along with the foreign CDT B toxin

While changes in biomarker levels thought to reflect changes in the underlying disease pathology have been used as a primary measure of successful treatment (e.g., as with anti-amyloid therapies), such outcomes may not necessarily correlate with the goal of actually helping people living with AD/ADRD along with their family members and care partners

XtalPi, in collaboration with Eli Lilly, applies AI and quantum physics to predict molecular properties, including crystal structures of small molecules

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