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The CG portion of GSH anchors the two adjacent protomers via not only these salt bridges, but also by additional H-bonding interactions with Y231 of protomer A and the carbonyl oxygen of W154 of protomer B via a bridging water molecule

[1] The pharmacokinetic profile of semaglutide contributes to its once-weekly dosing convenience but also has implications for overdose scenarios

10.1016/j.lfs.2022.120861 20 AtarashiK.TanoueT.ShimaT.ImaokaA.KuwaharaT.MomoseY.et al

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