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They have come into the limelight after a large double-blinded study published in NEJM, showed an average 14.9% decrease in weight in obese patients given semaglutide on top of lifestyle modifications, compared to 2.4% in the control arm (see research summary at end)

Type 2 diabetes (90%) is the most frequent form and usually occurs as a result of obesity and lack of exercise, but some people are genetically more at risk than others

Weight loss with Semaglutide GLP-1 varies depending on individual factors such as dosage, adherence to lifestyle changes, and overall health

Retatrutide is also a synthetic peptide, developed by Eli Lilly as a potential injectable medicine