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Thyroid Tumors: Rodent Risk, Human Precaution In animal studies, GLP-1s have been linked to C-cell tumors of the thyroid, including medullary thyroid carcinoma (MTC)

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Enteroendocrine cells (EEC) comprise approximately 1% of the intestinal epithelium, but secrete more than 30 different peptide hormones, which makes them the largest endocrine system in the whole body (Worthington 2015)